3. Biomaterials for bone tissue-engineering Essay

3. Biomaterials for bone tissue-engineering - Essay ExampleOsseointegration means the ability to conflate into surrounding bones. The noble-minded condition is that the tissue should be reabsorbed and may be even replaced by the consistences own regenerated biological tissues.Bioactive inorganic materials standardised tricalcium phosphate, HA, bioactive glasses shit a large energy to be re-absorbed. This is definitely one of the positive points of inorganic materials. But the main problem is their breakable nature. This brittle nature means that the fracture peevishness of the bones cannot b matched by these materials and thus is not ideal for picking heavy loads.Polymers such as collagen and hyaluronic acid are polymers which are interesting options for the use (Seeherman H, 2008).However they have weak mechanical properties and provide a possible risk of diseases if there is poor handling. Hydrogels are the smorgasbord of polymers which are creating great buzz about their use. They have many advantages including the one that chemical biofunctionalisation and cell encapsulation and sales talk are very straightforward.In order for the biomaterial to be like a real bone the toughness of a polymer needs to be combined with the compressive strength of an inorganic material (Hollinger, 2004). This improves their mechanical properties and degradation profiles. erstwhile the adequate biodegradable polymer has been selected the next step is to find a suitable processing technique. The processing methodological analysis must not adversely affect the biocompatibility or the chemical properties of the chosen materials. Through the years a variety of processing techniques have been developed. Some of them will be discussed here by us.Solvent plaster cast /Particulate Leaching This method consists of dispersing calibrated materials such as sodium chloride or organic materials like saccharine particles in a polymer solution. The dispersion is processed after thi s either by casting or by using the method of freeze drying which results in